Trabecular bone remodeling in the ageing mouse: a micro-multiphysics agent-based in silico model using single-cell mechanomics
D. Boaretti, F. C. Marques, C. Ledoux, A. Singh, J. J. Kendall, E. Wehrle, G. A. Kuhn, Y. D. Bansod, F. Schulte, R. Müller
This paper develops an in silico model of trabecular bone remodeling in aging mice, showing how changes in OPG, RANKL, and Scl levels affect bone volume fraction.
bioRxiv · Nov 16, 2022 · PreprintBioengineering