Dual role of E-cadherin in the regulation of invasive collective migration of mammary carcinoma cells
Y. Elisha, V. Kalchenko, Y. Kuznetsov, B. Geiger
This study shows that moderate E-cadherin levels in 4T1 cells promote collective migration and metastasis, while reduced levels enhance migration rate and suppress metastases.
bioRxiv · Jun 18, 2017Cancer Biology