Author

Y. Guiguen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 7

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:multiple species· 3 Assay:whole-genome sequencing· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:comparative / phylogenetic analysis· 2 Research Focus:development & morphogenesis· 2

Frequent Co-Authors

C. Klopp· 5 shared J. Bobe· 5 shared E. Jouanno· 4 shared C. Roques· 3 shared J. Lluch· 3 shared J. Pasquier· 3 shared J. Postlethwait· 3 shared L. Journot· 3 shared

Activity by Year

2017-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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5 shared papersEvolutionary Biology

C. Klopp

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7 papers

Recent·Most cited

Genome structures resolve the early diversification of teleost fishes

E. Parey, A. Louis, J. Montfort, O. Bouchez, C. Roques, C. Iampietro, J. Lluch, A. Castinel, C. Donnadieu, T. Desvignes, C. F. Bucao, E. Jouanno, M. Wen, S. Mejri, R. P. Dirks, , Y. Guiguen

The paper uses genome assemblies to resolve the evolutionary relationships among early diverging teleost lineages, placing Elopomorpha and Osteoglossomorpha as sister groups.

bioRxiv · Apr 7, 2022Evolutionary Biology

A 180 My-old female-specific genome region in sturgeon reveals the oldest known vertebrate sex determining system with undifferentiated sex chromosomes

H. Kuhl, Y. Guiguen, C. Hoehne, E. Keuz, C. Klopp, K. Du, C. Lopez-Roques, E. Santidrian Yebra-Pimentel, M. Ciorpac, J. Gessner, D. Holostenco, W. Kleiner, K. Kohlmann, D. Lamatsch, D. Prokopov, , M. Stoeck

The paper identifies a 180 My-old female-specific genome region in sturgeon, revealing an ancient undifferentiated sex chromosome system with ZZ/ZW sex determination.

bioRxiv · Oct 10, 2020Evolutionary Biology

Evolution of sex hormone binding globulins reveals early gene duplication at the root of vertebrates

Y. Guiguen, J. Pasquier, A. Fostier, J. Bobe

The paper identifies Shbgb as a novel sex hormone-binding globulin gene with gonadal expression, showing that Shbg genes originated from a whole genome duplication at the vertebrate root, followed by losses and tissue specialization.

bioRxiv · Jul 2, 2020Evolutionary Biology

The rise and fall of the ancient northern pike master sex determining gene

Q. Pan, R. Feron, E. Jouanno, H. Darras, A. Herpin, B. F. Koop, E. Rondeau, F. W. Goetz, W. A. Larson, L. Bernatchez, M. Tringali, S. S. Curran, E. Saillant, G. P. J. Denys, F. A. von Hippel, , Y. Guiguen

The paper traces the evolution of sex determination in northern pike, revealing an ancient origin of the master sex-determining gene and recent transitions including Y-chromosome loss.

bioRxiv · May 31, 2020Evolutionary Biology

Identification of the master sex determining gene in Northern pike (Esox lucius) reveals restricted sex chromosome differentiation

Q. Pan, R. Feron, A. Yano, R. Guyomard, E. Jouanno, E. Vigouroux, M. Wen, J.-M. Busnel, J. Bobe, J.-P. Concordet, H. Parrinello, L. Journot, C. Klopp, J. Lluch, C. Roques, , Y. Guiguen

The paper identifies and functionally validates an ancient duplicated anti-Mullerian hormone gene as the master sex determining gene in Northern pike, revealing limited sex chromosome differentiation.

bioRxiv · Feb 13, 2019Evolutionary Biology

Double Maternal Effect: Duplicated Nucleoplasmin 2 Genes, npm2a And npm2b, Are Shared By Fish And Tetrapods, And Have Distinct And Essential Roles In Early Embryogenesis

C. T. Cheung, J. Pasquier, A. Bouleau, T.-V. Nguyen, F. Chesnel, Y. Guiguen, J. Bobe

This paper identifies two duplicated npm2 genes, npm2a and npm2b, in vertebrates, showing their evolutionary origins and distinct essential roles in early embryogenesis.

bioRxiv · Jun 19, 2017Evolutionary Biology

Evolution of gene expression after whole-genome duplication: new insights from the spotted gar genome

J. Pasquier, I. Braasch, P. Batzel, C. Cabau, J. Montfort, T. Nguyen, E. Jouanno, C. Berthelot, C. Klopp, L. Journot, J. Postlethwait, Y. Guiguen, J. Bobe

The paper analyzes gene expression evolution after whole-genome duplication in teleost fish using the spotted gar genome and PhyloFish data, showing rapid fate determination of duplicates and ongoing functional divergence.

bioRxiv · Jun 19, 2017Evolutionary Biology