Disordered C-terminal domain drives spatiotemporal confinement of RNAPII to enhance search for chromatin targets
Y. H. Ling, Z. Ye, C. Liang, C. Yu, G. Park, J. L. Corden, C. Wu
The paper shows that the disordered C-terminal domain of RNAPII confines its diffusion to a subnuclear region, enhancing target search efficiency in yeast.
bioRxiv · Jul 31, 2023Cell Biology