K. M. Chan

Effects of Repeat Test Exposure on Gait Parameters in Naive Lewis Rats

This study shows repeated gait testing in rats affects gait parameters, with exposure being a major factor over age and weight.

Cell cycle regulation of the psoriasis associated gene CCHCR1 by transcription factor E2F1

This study identifies E2F1 as a transcription factor regulating CCHCR1 expression through a bidirectional promoter with TCF19 during the G1/S cell cycle transition.

ATF3 Preserves Skeletal Muscle Stem Cell Quiescence by Preventing Precocious Activation

This study identifies ATF3 as a key regulator that preserves skeletal muscle stem cell quiescence by preventing premature activation and maintaining genome stability.

Phenethylamine-producing gut bacteria induces diarrhea-predominant irritable bowel syndrome by increasing serotonin biosynthesis

This study identifies Ruminococcus gnavus as a gut bacterium that contributes to IBS-D by increasing serotonin biosynthesis through phenethylamine production.

Cytoprotective effects of (E)-N-(2-(3, 5-dimethoxystyryl) phenyl) furan-2-carboxamide (BK3C231) against 4-nitroquinoline 1-oxide-induced damage in CCD-18Co human colon fibroblast cells

This study investigates the cytoprotective effects of BK3C231 against 4NQO-induced DNA and mitochondrial damage in CCD-18Co cells, showing reduced DNA breaks, micronuclei, and mitochondrial dysfunction.