Landscape of tumor-infiltrating immune cells in human immunogenic cancers: B cells are inversely associated with CD8T cells, but positively correlated with Treg cells
Y. K. Chae, W. Bae, M. Jung, Y. S. Kim, J. F. Anker, K. Tamragouri, M. Matsangou, F. J. Giles
The paper analyzes immune cell infiltration in six cancers, finding activated B cells correlate with reduced CD8 T cell infiltration and increased Treg cells, suggesting B cells may inhibit T cell activity.
bioRxiv · May 17, 2019 · PreprintCancer Biology