Predicting drug polypharmacology from cell morphology readouts using variational autoencoder latent space arithmetic
Y. L. Chow, S. Singh, A. E. Carpenter, G. P. Way
This paper uses VAEs to predict drug polypharmacology from cell morphology data and gene expression, finding that beta-VAE and MMD-VAE better disentangle morphology signals.
bioRxiv · Sep 2, 2021Pharmacology & Toxicology