Author

G. P. Way

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:human· 4 Approach:deep learning· 3 Assay:imaging· 3 Assay:bulk RNA-seq· 2 Research Focus:clustering· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2

Frequent Co-Authors

A. E. Carpenter· 2 shared C. S. Greene· 2 shared S. Singh· 2 shared A. A. Hippen· 1 shared A. Berchuck· 1 shared A. Campbell· 1 shared A. P. Wiita· 1 shared A. Y. Berman· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCancer Biology

A. E. Carpenter

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Author profile →

5 papers

Recent·Most cited

Toward generalizable phenotype prediction from single-cell morphology representations

J. Tomkinson, R. Kern, C. Mattson, G. P. Way

This paper predicts single-cell phenotypes from nuclear morphology using pre-labeled microscopy data, achieving high accuracy for some phenotypes but facing generalizability challenges.

bioRxiv · Mar 13, 2024 · PreprintCell Biology

Molecular subtypes of high grade serous ovarian cancer across racial groups and gene expression platforms

N. R. Davidson, M. E. Barnard, A. A. Hippen, A. Campbell, C. Johnson, G. P. Way, B. K. Dalley, A. Berchuck, L. A. Salas, L. C. Peres, J. R. Marks, J. M. Schildkraut, C. S. Greene, J. A. Doherty

This study identifies molecular subtypes of high-grade serous ovarian cancer across racial groups and gene expression platforms, finding similar subtype-specific survival rates despite differences in subtype prevalence.

bioRxiv · Nov 1, 2023Cancer Biology

High-content microscopy reveals a morphological signature of bortezomib resistance

M. E. Kelley, A. Y. Berman, D. R. Stirling, B. A. Cimini, Y. Han, S. Singh, A. E. Carpenter, T. M. Kapoor, G. P. Way

The paper identifies a morphological signature of bortezomib resistance using high-content microscopy and shows it predicts treatment response in independent cell lines.

bioRxiv · May 2, 2023Cancer Biology

Predicting drug polypharmacology from cell morphology readouts using variational autoencoder latent space arithmetic

Y. L. Chow, S. Singh, A. E. Carpenter, G. P. Way

This paper uses VAEs to predict drug polypharmacology from cell morphology data and gene expression, finding that beta-VAE and MMD-VAE better disentangle morphology signals.

bioRxiv · Sep 2, 2021Pharmacology & Toxicology

Integrated Phosphoproteomics and Transcriptional Classifiers Reveal Hidden RAS Signaling Dynamics in Multiple Myeloma

Y.-H. T. Lin, G. P. Way, B. G. Barwick, M. C. Mariano, M. Marcoulis, I. D. Ferguson, C. Driessen, L. H. Boise, C. S. Greene, A. P. Wiita

The paper uses phosphoproteomics and transcriptomics to analyze RAS signaling in multiple myeloma, identifying distinct signaling patterns and clinical outcomes associated with NRAS and KRAS mutations.

bioRxiv · Feb 28, 2019Cancer Biology