Author

Y. Le Guen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:clinical cohort / trial· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Chatziioannou· 1 shared A. Jouannic· 1 shared A. S. Durairaj· 1 shared C. M. Muir· 1 shared C. Mastrokalou· 1 shared C. Ricordel· 1 shared C. S. Kwak· 1 shared C.-H. Hsieh· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Chatziioannou

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A Mitochondrial Inside-Out Iron-Calcium Signal Reveals Drug Targets for Parkinsons Disease

V. Bharat, A. S. Durairaj, R. Vanhauwaert, L. Li, C. M. Muir, S. Chandra, C. S. Kwak, Y. Le Guen, P. Nandakishore, C.-H. Hsieh, S. E. Rensi, R. Altman, M. D. Greicius, L. Feng, X. Wang

This study identifies a mitochondrial iron-calcium signaling mechanism in Parkinson's disease and discovers drug targets using Miro1-based screens and genetic analysis.

bioRxiv · Oct 30, 2022Cell Biology

Genomic characteristics and clinical significance of CD56+ Circulating Tumor Cells in Small Cell Lung Carcinoma

C. Ricordel, L. Chaillot, E.-I. Vlachavas, M. Logotheti, A. Jouannic, T. Desvallees, G. Lecuyer, M. Aubry, G. Kontogianni, C. Mastrokalou, F. Jouan, U. Jarry, R. Corre, Y. Le Guen, T. Guillaudeux, , R. Pedeux

This study isolates and analyzes CD56+ circulating tumor cells in SCLC, finding they have distinct genomic features and are associated with disease extension.

bioRxiv · Apr 30, 2022Cancer Biology