Single-cell Transcriptomics reveals multi-step adaptations to endocrine therapy
S. P. Hong, T. E. Chan, Y. Lombardo, G. Corleone, N. Rotmensz, G. Pruneri, K. R. McEwen, C. R. Coombes, I. Barozzi, L. Magnani
This study uses single-cell transcriptomics to identify pre-adapted cells that undergo reprogramming to develop resistance to endocrine therapy in breast cancer.
bioRxiv · Dec 2, 2018Cancer Biology