Author

G. Corleone

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

C. Cortile· 2 shared F. De Nicola· 2 shared G. Pruneri· 2 shared L. Magnani· 2 shared M. Fanciulli· 2 shared A. Mengarelli· 1 shared A. Pitisci· 1 shared A. Saiakhova· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCancer Biology

C. Cortile

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Enhancer plasticity sustains oncogenic transformation and progression of B-Cell Acute Lymphoblastic leukemia.

G. Corleone, C. Sorino, M. Caforio, S. Di Giovenale, F. De Nicola, V. Bertaina, A. Pitisci, C. Cortile, F. Locatelli, V. Folgiero, M. Fanciulli

This study shows enhancer plasticity drives oncogenic transformation and relapse in B-Cell Acute Lymphoblastic Leukemia by dynamically changing during disease progression.

bioRxiv · May 18, 2022Cancer Biology

AATF/Che-1, a new component of paraspeckles, controls R-loops formation and Interferon activation in Multiple Myeloma.

T. Bruno, G. Corleone, C. Cortile, F. de Nicola, V. Catena, F. Fabbretti, S. Gumenyuk, F. Pisani, A. Mengarelli, C. Passananti, M. Fanciulli

This study identifies Che-1/AATF as a paraspeckle component that regulates R-loop formation and interferon activation in multiple myeloma, linking R-loops to disease progression and poor prognosis.

bioRxiv · Aug 4, 2021 · PreprintCell Biology

Single-cell Transcriptomics reveals multi-step adaptations to endocrine therapy

S. P. Hong, T. E. Chan, Y. Lombardo, G. Corleone, N. Rotmensz, G. Pruneri, K. R. McEwen, C. R. Coombes, I. Barozzi, L. Magnani

This study uses single-cell transcriptomics to identify pre-adapted cells that undergo reprogramming to develop resistance to endocrine therapy in breast cancer.

bioRxiv · Dec 2, 2018Cancer Biology

Enhancers mapping uncovers phenotypic heterogeneity and evolution in patients with luminal breast cancer.

D. Patten, G. Corleone, B. Gyorffy, E. Erdos, A. Saiakhova, K. Goddard, A. Vingiani, S. Shousha, L. S. Pongor, D. Hadjiminas, G. Schiavon, P. Barry, C. Palmieri, C. Coombes, P. Scacheri, , L. Magnani

This study maps enhancers in luminal breast cancer to reveal phenotypic heterogeneity and its evolutionary dynamics during treatment.

bioRxiv · Sep 26, 2017Cancer Biology