Coordination of phage genome degradation versus host genome protection by a bifunctional restriction-modification enzyme visualized by CryoEM
B. W. Shen, J. D. Quispe, Y. Luyten, B. C. McGeough, R. D. Morgan, B. L. Stoddard
This study visualizes how a bifunctional restriction-modification enzyme coordinates DNA methylation and cleavage using CryoEM, revealing the structural basis for its dual function.
bioRxiv · Jan 6, 2021Biochemistry