ImmunologybioRxivPreprint
Polyamine Metabolism Regulates the T Cell Epigenome Through Hypusination
D. J. Puleston, F. Baixauli, D. E. Sanin…·E. L. Pearce
This study shows that polyamine metabolism, specifically through hypusination, is essential for maintaining T cell subset identity by regulating the epigenome and transcriptional programs.