Author

Y. Ohara

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Organism:human· 4 Assay:metabolomics· 4 Approach:statistical model· 4 Research Focus:gene regulatory network inference· 2 Approach:experimental assay· 1

Frequent Co-Authors

A. Azizian· 4 shared H. Cawley· 4 shared H. Liu· 4 shared J. Gaedcke· 4 shared N. Hanna· 4 shared P. Moreno· 4 shared S. P. Hussain· 4 shared S. Yang· 4 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersCancer Biology

A. Azizian

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4 papers

Recent·Most cited

ADRA2A promotes the classical/progenitor subtype and reduces disease aggressiveness of pancreatic cancer

P. Moreno, Y. Ohara, A. J. Craig, H. Liu, S. Yang, L. Zhang, G. Panigrahi, T. H. Dorsey, H. Cawley, A. Azizian, J. Gaedcke, M. Ghadimi, N. Hanna, S. P. Hussain

This study identifies ADRA2A as a gene that promotes the classical/progenitor subtype and reduces aggressiveness in pancreatic cancer by altering transcriptome and metabolome profiles.

bioRxiv · Mar 12, 2024Cancer Biology

LMO3 is a suppressor of the basal-like/squamous PDAC subtype and reduces disease aggressiveness of pancreatic cancer through glycerol 3-phosphate metabolism

Y. Ohara, A. J. Craig, H. Liu, S. Yang, P. Moreno, T. H. Dorsey, H. Cawley, A. Azizian, J. Gaedcke, M. Ghadimi, N. Hanna, S. Ambs, S. P. Hussain

This study identifies LMO3 as a suppressor of the aggressive basal-like/squamous PDAC subtype, showing it reduces disease aggressiveness through modulation of glycerol 3-phosphate metabolism.

Carcinogenesis · Feb 15, 2024Peer-reviewedCancer Biology

ELAPOR1 induces the classical/progenitor subtype and contributes to reduced disease aggressiveness through metabolic reprogramming in pancreatic cancer

Y. Ohara, A. J. Craig, H. Liu, S. Yang, P. Moreno, T. H. Dorsey, H. Cawley, A. Azizian, J. Gaedcke, M. Ghadimi, N. Hanna, S. Ambs, S. P. Hussain

This study identifies ELAPOR1 as a tumor suppressor in pancreatic cancer, showing its association with reduced disease aggressiveness and a metabolic signature of the classical/progenitor subtype.

bioRxiv · Sep 23, 2023Cancer Biology

SERPINB3 induces the basal-like/squamous subtype and enhances disease progression in pancreatic cancer

Y. Ohara, W. Tang, H. Liu, S. Yang, T. H. Dorsey, H. Cawley, P. Moreno, A. Azizian, J. Gaedcke, B. M. Ghadimi, N. Hanna, S. Ambs, S. P. Hussain

This study identifies SERPINB3 as a marker for the basal-like/squamous subtype of pancreatic cancer, showing it promotes invasion, metastasis, and metabolic reprogramming.

bioRxiv · Mar 29, 2023Cancer Biology