Author

Y. Pechersky

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Assay:cryo-EM· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1 Organism:virus· 1

Frequent Co-Authors

D. E. Shaw· 2 shared Q. Wang· 2 shared A. C. Pan· 1 shared B. Malone· 1 shared E. A. Campbell· 1 shared E. Llewellyn· 1 shared E. T. Eng· 1 shared J. Chen· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersBiophysics

D. E. Shaw

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2 papers

Recent·Most cited

Ensemble cryo-electron microscopy reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex

J. Chen, Q. Wang, B. Malone, E. Llewellyn, Y. Pechersky, K. Maruthi, E. T. Eng, J. K. Perry, E. A. Campbell, D. E. Shaw, S. A. Darst

This study uses cryo-EM and simulations to identify four conformational states of the nsp13 helicase in the SARS-CoV-2 RTC, revealing an allosteric mechanism for switching between RNA synthesis and backtracking.

bioRxiv · Nov 10, 2021 · PreprintBiophysics

Structural mechanism for Bruton’s tyrosine kinase activation at the cell membrane

Q. Wang, Y. Pechersky, S. Sagawa, A. C. Pan, D. E. Shaw

This study uses molecular dynamics simulations to show that PIP3 stabilizes Btk dimerization at the cell membrane, which is critical for Btk activation.

bioRxiv · Apr 18, 2018Biophysics