Systematic assessment of the accuracy of subunit counting in biomolecular complexes using automated single molecule brightness analysis
J. S. H. Danial, Y. Quintana, U. Ros, R. Shalaby, E. G. Margheritis, S. Chumpen, C. Ungermann, A. J. Garcia-Saez, K. Cosentino
This paper develops an automated computational pipeline to assess subunit counting accuracy in biomolecular complexes using single molecule brightness analysis across simulated and experimental data.
bioRxiv · Nov 22, 2021Biophysics