Author

K. Cosentino

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Assay:imaging· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A. J. Garcia-Saez· 2 shared E. G. Margheritis· 2 shared J. S. H. Danial· 2 shared A. P. Gilmore· 1 shared C. Ungermann· 1 shared D. D. Newmeyer· 1 shared G. Hummer· 1 shared H. Veit· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiophysics

A. J. Garcia-Saez

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structure and regulation of GSDMD pores at the plasma membrane of pyroptotic cells

S. Kappelhoff, M. Holtmannspoetter, S. L. Schaefer, E. G. Margheritis, H. Veit, J. S. H. Danial, S. Strauss, R. Franzkoch, O. E. Psathaki, R. Jungmann, R. Kurre, G. Hummer, J. Piehler, K. Cosentino

The paper visualizes GSDMD nanostructures at the plasma membrane of pyroptotic cells and identifies PI(3,4,5)P3 as a regulator of pore formation.

bioRxiv · Oct 24, 2023 · PreprintBiophysics

Systematic assessment of the accuracy of subunit counting in biomolecular complexes using automated single molecule brightness analysis

J. S. H. Danial, Y. Quintana, U. Ros, R. Shalaby, E. G. Margheritis, S. Chumpen, C. Ungermann, A. J. Garcia-Saez, K. Cosentino

This paper develops an automated computational pipeline to assess subunit counting accuracy in biomolecular complexes using single molecule brightness analysis across simulated and experimental data.

bioRxiv · Nov 22, 2021Biophysics

Bax mitochondrial residency is more critical than Bax oligomerization for apoptosis

T. Kuwana, L. King, K. Cosentino, J. Suess, A. J. Garcia-Saez, A. P. Gilmore, D. D. Newmeyer

This study shows that Bax mitochondrial residency, not oligomerization, is critical for apoptosis, using mutants in cell-free and cellular systems.

bioRxiv · Apr 29, 2019 · PreprintCell Biology