Author

E. G. Margheritis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:imaging· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Approach:microscopy & imaging analysis· 1 Approach:statistical model· 1

Frequent Co-Authors

J. S. H. Danial· 2 shared K. Cosentino· 2 shared A. J. Garcia-Saez· 1 shared C. Ungermann· 1 shared G. Hummer· 1 shared H. Veit· 1 shared J. Piehler· 1 shared M. Holtmannspoetter· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiophysics

J. S. H. Danial

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Author profile →

2 papers

Recent·Most cited

Structure and regulation of GSDMD pores at the plasma membrane of pyroptotic cells

S. Kappelhoff, M. Holtmannspoetter, S. L. Schaefer, E. G. Margheritis, H. Veit, J. S. H. Danial, S. Strauss, R. Franzkoch, O. E. Psathaki, R. Jungmann, R. Kurre, G. Hummer, J. Piehler, K. Cosentino

The paper visualizes GSDMD nanostructures at the plasma membrane of pyroptotic cells and identifies PI(3,4,5)P3 as a regulator of pore formation.

bioRxiv · Oct 24, 2023 · PreprintBiophysics

Systematic assessment of the accuracy of subunit counting in biomolecular complexes using automated single molecule brightness analysis

J. S. H. Danial, Y. Quintana, U. Ros, R. Shalaby, E. G. Margheritis, S. Chumpen, C. Ungermann, A. J. Garcia-Saez, K. Cosentino

This paper develops an automated computational pipeline to assess subunit counting accuracy in biomolecular complexes using single molecule brightness analysis across simulated and experimental data.

bioRxiv · Nov 22, 2021Biophysics