An anti-cancer binary system activated by bacteriophage HK022 Integrase
A. Elias, I. Spector, N. Gritsenko, Y. Zilberstein, R. Gorovits, G. Prag, M. Kolot
This paper develops a new binary cancer gene therapy system using HK022 bacteriophage integrase to specifically activate DTA expression in cancer cells, showing higher efficacy and specificity than a conventional system.
bioRxiv · Jun 12, 2017Cancer Biology