Sensitive and specific miRNA in situ hybridization using partially methylated phosphotriester antisense DNA probes
P.-H. Wang, C.-W. Chang, T. Z. Jia, B. C.-M. Tan, Y.-H. Chi, W.-Y. Chen
This study demonstrates that partially methylated nDNA probes enhance miRNA detection specificity and sensitivity in in situ hybridization compared to conventional DNA probes.
bioRxiv · Jun 12, 2022 · PreprintBioengineering