The mGluR5 Agonist, CHPG, Enhances Numbers of Differentiated Human Oligodendrocytes
Yangyang Huang, Celine Geywitz, Anjalika Bandaru, Ian A. Glass, Lucas Schirmer, Hiroko Nobuta, Cheryl F. Dreyfus
This study shows that CHPG increases differentiation of human oligodendrocyte precursor cells and upregulates mGluR5 in MS astrocytes, suggesting potential therapeutic applications.
bioRxiv · May 31, 2025 · PreprintNeuroscience