Yeast Ixr1 mediates the DNA replication stress response through it HMGB DNA binding domains and interaction with checkpoint Mrc1
Siying Teng, Yi Wang, Jingyuan Jiang, Mengyuan Li, Ying-Xin Liu, Yangying Guan, Anhui Wei, Zhongyi Cong, Xinmin Zhang
This study identifies Ixr1's role in DNA replication stress response through its interaction with Mrc1 and DNA binding domains, showing sensitivity to HU and gene expression changes.
bioRxiv · May 30, 2023 · PreprintGenetics