Author

Yangyu Wu

Yale University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Organism:mouse· 1 Research Focus:software / tool· 1

Frequent Co-Authors

A Prem Kumar· 1 shared Allen Chunlong GuoiD· 1 shared Emma AmjadiD· 1 shared Erin Smith· 1 shared Fanhao MengiD· 1 shared Haibin LiuiD· 1 shared Han-A ParkiD· 1 shared Huaican Xu· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

A Prem Kumar

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2 papers

Recent·Most cited

Bedaquiline inhibits the ATP synthase leak channel and prevents glutamate-induced neuronal death

A Prem Kumar, Olesia Lunko, Erin Smith, Ikram Mezghani, Subhash Eedarapalli, Yangyu Wu, Khondoker Adeba Ferdous, Emma Amjad, Han-A Park, Nelli Mnatsakanyan

This paper shows that bedaquiline inhibits the ATP synthase c-subunit leak channel and prevents glutamate-induced neuronal death in primary hippocampal neurons.

Biophysical Reports · May 12, 2026Peer-reviewedBiophysics

SMART: An Integrated Platform Revolutionizing Cryo-Electron Microscopy Workflow from Data Acquisition to Atomic Modeling

Haibin Liu, Yangyu Wu, Wenpeng Zhang, Huaican Xu, Zhenqian Guo, Fanhao Meng, Xinyu Men, Allen Chunlong Guo

SMART is an integrated cryo-EM platform that automates data acquisition, reconstruction, and atomic modeling using AI, enabling users to generate high-resolution structures like TRPML1 at 2.1 Å resolution.

bioRxiv · Jun 5, 2025 · PreprintBioinformatics