The Conformation of the Complementary Strand and the Deformation of the DNA Groove upon DDB2 Binding Justifies the Different Repair Rates for Cyclobutane Pyrimidine Dimers.
Yani Kedjar, Cécilia Hognon, Thierry Douki, Elise E. Dumont, Antonio Monari
This study shows that DDB2 binding causes different DNA deformations depending on the cyclobutane pyrimidine dimer type, which explains the varying repair rates observed in human cells.
Photochemical & Photobiological Sciences · Sep 1, 2026Peer-reviewedBiophysics