Alcohol induces p53-mediated apoptosis in neural crest by stimulating the AMPK-mediated suppression of TORC1, p70/S6K, and ribosomal biogenesis.
Yanping Huang, George R. Flentke, Susan M. Smith
This study shows alcohol induces p53-mediated apoptosis in neural crest cells by activating AMPK, which suppresses TORC1, p70/S6K, and ribosomal biogenesis.
Reproductive Toxicology · Jul 4, 2024Peer-reviewedPharmacology & Toxicology