Single-cell transcriptomics for the 99.9% of species without reference genomes
Olga Borisovna Botvinnik, Venkata N. P. Vemuri, N. Tessa Pierce‐Ward, Phoenix Logan, Saba Nafees, Lekha Sree Karanam, Kyle J. Travaglini, Camille Ezran, Lili Ren, Yanyi Juang, Jianwei Wang, Jianbin Wang, C. Titus Brown
This paper introduces Kmermaid and Orpheum to enable scRNA-seq analysis in species without reference genomes by detecting cell type-specific sequences without gene annotations.
bioRxiv · Jul 9, 2021 · PreprintBioinformatics