BMSC-Laden PEGDA/HAMA Dual-Crosslinked Hydrogels with Distinct Stiffness Profiles for Osteochondral Defect Repair
Maojiang Lyu, Xin Guo, Liqi Ng, Yi Sun, Jianjing Lin, Xu Zhang, XinTao Zhang, YaoHua He
This study develops a BMSC-laden PEGDA/HAMA hydrogel with distinct stiffness profiles to repair osteochondral defects, showing improved defect filling and subchondral bone remodeling in vivo but limited collagen type II expression.
bioRxiv · May 27, 2026 · PreprintBioengineering