VarDrug: A Machine Learning Approach for Variant-Drug Interaction, Application to Drugs for Psychiatric Disorders
MohammadReza KarimiNejad, Narges SangaraniPour, Yasmin Naji, Mohammad Shafiezadeh, Seyed Reza Tavakoli, Siavash Ahmadi, Babak Hossein Khalaj, Mohammad Hossein Rohban
VarDrug predicts variant-drug interactions using machine learning on PharmGKB data, achieving 90% F1 score for psychiatric disorder applications.
medRxiv · Jun 28, 2025 · PreprintGenetic & Genomic Medicine