Author

Mohammadreza Kariminejad

Sharif University of TechnologyORCID 0009-0007-0064-1405Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:GWAS summary statistics· 1 Approach:machine learning (classical)· 1 Approach:statistical model· 1

Frequent Co-Authors

Ali AkbariiD· 1 shared Alison R. BartoniD· 1 shared Alissa MittnikiD· 1 shared Alkes L. PriceiD· 1 shared Annabel PerryiD· 1 shared Babak Hossein KhalajiD· 1 shared David ReichiD· 1 shared Eric S. LanderiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperEvolutionary Biology

Ali AkbariORCID

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2 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintJun 28, 2025

VarDrug: A Machine Learning Approach for Variant-Drug Interaction, Application to Drugs for Psychiatric Disorders

MohammadReza KarimiNejad, Narges SangaraniPour, Yasmin Naji…·Mohammad Hossein Rohban

VarDrug predicts variant-drug interactions using machine learning on PharmGKB data, achieving 90% F1 score for psychiatric disorder applications.

DOI 10.1101/2025.06.28.25330468

humanGWAS summary statistics

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Evolutionary BiologybioRxivPreprintSep 14, 2024

Pervasive findings of directional selection realize the promise of ancient DNA to elucidate human adaptation

Ali Akbari, Alison R. Barton, Steven Gazal…·David Reich

This paper detects widespread directional selection in ancient DNA data, identifying 347 genome-wide significant loci and linking them to traits like body fat, skin color, and cognitive performance.

53 citations

humanDNA methylation

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