Monocyte-Lymphocyte Cross-Communication Via Soluble CD163 Directly Links Innate Immune System Activation And Adaptive Immune System Suppression Following Ischemic Stroke
Grant C. O’Connell, Connie S. Tennant, Noelle Lucke-Wold, Yasser Kabbani, Abdul Tarabishy, Paul David Chantler, Taura L. Barr
This study shows that soluble CD163 from activated monocytes suppresses lymphocytes after ischemic stroke, linking innate immune activation to adaptive immune suppression.
Scientific Reports · Oct 5, 2017Peer-reviewedNeuroscience