HLA-B51 induces IFN-γproduction in human natural killer cells
Yasuhiro Omata, Hiroko Hayakawa, Kojiro Sato
This study shows HLA-B51 activates human NK cells to produce IFN-γ, with KLRK1 as a key receptor, while IL-2 signals override HLA-B51 effects in some NK cell lines.
bioRxiv · May 6, 2026 · PreprintImmunology