Mitochondrial double-stranded RNAs as a pivotal mediator in the pathogenesis of Sjogrens syndrome
Jimin Yoon, Min-Seok Lee, Ahsan Ausaf Ali, Ye Rim Oh, Yong Seok Choi, Sujin Kim, Namseok Lee, Se Gwang Jang, Seung‐Ki Kwok, Joon Young Hyon, Seunghee Cha, Yun Jong Lee, Sung Gap Im, Yoosik Kim
This study identifies mitochondrial double-stranded RNAs (mt-dsRNAs) as drivers of type I interferon responses and inflammatory phenotypes in Sjogrens syndrome.
bioRxiv · Sep 13, 2021 · PreprintMolecular Biology