The architecture of membrane structures involved in hepatitis C virus genome replication revealed in close-to-native conditions by cryo-electron tomography
Upasana M. Sykora, Thomas J. O’ Sullivan, Yehuda Halfon, Juan Fontana, Mark Harris
This study uses cryo-electron tomography to visualize HCV replication structures in near-native conditions, revealing densities within membranous vesicles that may represent viral replication machinery.
Journal of General Virology · Nov 6, 2025Peer-reviewedMicrobiology