Author

Upasana M. Sykora

University of LeedsORCID 0000-0001-6489-0952Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein structure prediction· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Antonio N. CalabreseiD· 1 shared Arindam DattaiD· 1 shared Elton ZeqirajiD· 1 shared Francesca ChandleriD· 1 shared Gemma C. Wildsmith· 1 shared Hirunika Perera· 1 shared Jordan LiburdiD· 1 shared Juan FontanaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

Antonio N. CalabreseORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedAug 11, 2026

Mechanism of K63-linked polyubiquitin recognition and cleavage by the BRCA1-A complex

Martina Foglizzo, Arindam Datta, Oksana Degtjarik…·Elton Zeqiraj

The paper investigates how the BRCA1-A complex recognizes and cleaves K63-linked polyubiquitin chains, revealing structural and functional mechanisms involved in DNA damage response.

1 citation

experimental assaywet-lab / biochemical assay

𝕏 PostBluesky

MicrobiologyJournal of General VirologyPeer-reviewedNov 6, 2025

The architecture of membrane structures involved in hepatitis C virus genome replication revealed in close-to-native conditions by cryo-electron tomography

Upasana M. Sykora, Thomas J. O’ Sullivan, Yehuda Halfon…·Mark Harris

This study uses cryo-electron tomography to visualize HCV replication structures in near-native conditions, revealing densities within membranous vesicles that may represent viral replication machinery.

1 citation

humancryo-EM

𝕏 PostBluesky