Yih-Chii Hwang

Mesenchymal Stem Cell-Mediated Intercellular Communication: Mapping the Interactome for Skeletal Muscle Homeostasis and Regeneration

The paper constructs a comprehensive FAP interactome in skeletal muscle using single-cell RNA sequencing and computational analysis, identifying novel signaling pathways and validating their roles in homeostasis and regeneration.

Towards a Comprehensive Variation Benchmark for Challenging Medically-Relevant Autosomal Genes

This paper creates a comprehensive benchmark for challenging medically-relevant autosomal genes, improving variant recall from 8% to 100% by addressing reference-specific false duplications.

Open-source mapping and variant calling for large-scale NGS data from original base-quality scores

The paper defines an open-source, lossless read-mapping protocol for NGS data and demonstrates direct variant calling without base quality score recalibration.

HIPPIE2: a method for fine-scale identification of physically interacting chromatin regions

HIPPIE2 identifies physically interacting chromatin regions with high resolution and reproducibility across human cell lines.