Highly precise base editing with CC context-specificity using engineered human APOBEC3G-nCas9 fusions
Zhiquan Liu, Siyu Chen, Huanhuan Shan, Yingqi Jia, Mao Chen, Yuning Song, Liangxue Lai, Zhanjun Li
This paper develops a base editor with CC context-specificity and relaxed PAM recognition to improve precision and targeting scope for gene modification.
BMC Biology · Aug 31, 2020Peer-reviewedMolecular Biology