Ependymocytes control cerebrospinal fluid flow to the peripheral organs through periaxonal pathway
Xinyu Li, Siman Wang, Dianjun Zhang, Yuliang Feng, Yingyu Liu, Weiyang Yu, Shu Li, Lulu Cui, Tibor Harkany, Alexei Verkhratsky, Maosheng Xia, Baoman Li
The paper identifies a novel mechanism by which ependymocytes regulate cerebrospinal fluid (CSF) flow from the central nervous system to peripheral organs via the periaxonal pathway, mediated by serotonin signaling and F-actin polymerization.
bioRxiv · Oct 9, 2023 · PreprintNeuroscience