Comparative evaluation of reference genomes and cell-type annotation frameworks for single-nucleus transcriptomic analysis in apple
Sun Hu, Yiqi Liu, Yujie Zhao, Bo Li, Yawen Shen, Yoshiharu Mimata, Kunxi Zhang, Pengbo Hao, Jiangli Shi, Zhiwei Luo, Wenxiu Ye, Xianbo Zheng, Jian Jiao
The paper evaluates reference genomes and cell-type annotation frameworks for snRNA-seq in apple, finding that GDDH13 provides the best mapping and annotation performance, and that combining marker genes with cross-species frameworks improves cell-type identification.
Agriculture Communications · Jun 29, 2026Peer-reviewedBioinformatics