Single Molecule Diffusion Studies Reveal Rapid Translations Across Target Membrane Surfaces for both p40Phox PX domain and Class III PI3K VPS34 Complex 1, the Autophagy Lipid Kinase
Lucas Lizardos, Yohei Ohashi, Anne Marie McCombs, Jefferson D Knight, Roger L Williams, Joseph J Falke
This paper uses single molecule tracking to study how p40Phox PX domain and VPS34 Complex 1 move across lipid bilayers, revealing electrostatic hopping and docking mechanisms.
bioRxiv · Nov 2, 2026 · PreprintBiophysics