Long read sequencing reveals a novel class of structural aberrations in cancers: identification and characterization of cancerous local amplifications
Yoshitaka Sakamoto, Liu Xu, Masahide Seki, Toshiyuki Yokoyama, Masahiro Kasahara, Yukie Kashima, Akihiro Ohashi, Yoko Shimada, Noriko Motoi, Katsuya Tsuchihara, Susumu S. Kobayashi, Takashi Kohno, Yuichi Shiraishi, Ayako Suzuki, Yutaka Suzuki
The paper identifies a novel class of structural aberrations in lung cancers using long-read sequencing and shows their occurrence in vivo and in cancer-related genes.
Genome Research · Sep 1, 2020Peer-reviewedGenomics