Author
National Cancer Center Exploratory Oncology Research & Clinical Trial CenterORCID 0000-0001-7507-2349Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Shunsuke A. Sakai, Ryosuke Nomura, Masaki Ohira…·Riu Yamashita
SPATNIC is a variational autoencoder that identifies cancer cells from spatial and single-cell transcriptomic data in colorectal cancer, outperforming existing tools and identifying a rare cancer stem cell population.
Kyoko Kurihara, Shunsuke A. Sakai, Kentaro Sawada…·Riu Yamashita
The paper analyzes gut microbiota changes across 264 cancer patients treated with 22 anticancer drugs, finding drug-specific and treatment-related microbiota alterations.
Shunsuke A. Sakai, Masayuki Okumura, Y Morinaga…·Shun‐Ichiro Kageyama
The paper identifies POSTN-expressing cancer-associated fibroblasts (CAFs) linked to chemoradiotherapy resistance in rectal cancer using spatial multi-omics data.
Ryosuke Nomura, Shunsuke A. Sakai, Shun‐Ichiro Kageyama…·Riu Yamashita
SCOMV classifies cell and gene spatial patterns and identifies spatially differential genes in spatial transcriptomic data without prior knowledge.
Shunsuke A. Sakai, Ryosuke Nomura, Satoi Nagasawa…·Riu Yamashita
The paper introduces SpatialKNife, a toolkit for analyzing single-cell spatial omics data to estimate spatiotemporal pathological mechanisms in microenvironments.
Yoshitaka Sakamoto, Liu Xu, Masahide Seki…·Yutaka Suzuki
The paper identifies a novel class of structural aberrations in lung cancers using long-read sequencing and shows their occurrence in vivo and in cancer-related genes.