A gut-selective Axl Inhibitor Attenuates Intestinal Fibrosis in myofibroblast cell models and the Mouse S. Typhimurium Model in vivo
Yongjia Feng, Laura A. Johnson, Martin C. Clasby, Peter Higgins
This study tests a gut-selective Axl inhibitor, CCG264341, in vitro and in vivo models of intestinal fibrosis, finding it reduces fibrosis markers and Axl signaling.
bioRxiv · Mar 30, 2025 · PreprintImmunology