Author

Peter Higgins

University of MichiganORCID 0000-0003-1602-4341Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Immunology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Angeline WuiD· 1 shared Arash YunesiiD· 1 shared Barbara TreutleiniD· 1 shared Charlie J. ChildsiD· 1 shared Christopher J. AlteriiD· 1 shared Emily M. HollowayiD· 1 shared Hiroko Nagao‐Kitamoto· 1 shared Ian A. GlassiD· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperDevelopmental Biology

Angeline WuORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Immune phenotype-guided identification of disease-associated pathobionts in Crohn's disease

Hiroko Nagao‐Kitamoto, Kohei Sugihara, Sho Kitamoto, Shinya Ebihara, Yeji Kim, Kira L. Newman, Uxía Alonso Alonso, Takehiro Suzuki, Yoshiyuki Kioi, Arash Yunesi, Naohiro Inohara, Christopher J. Alteri, Phillip Minar, Lee A. Denson, Peter Higgins, , Nobuhiko Kamada

This study identifies IL-1β-inducing pathobionts in Crohn's disease that drive inflammation and may predict response to anti-TNF therapies.

bioRxiv · Apr 1, 2025 · PreprintImmunology

A gut-selective Axl Inhibitor Attenuates Intestinal Fibrosis in myofibroblast cell models and the Mouse S. Typhimurium Model in vivo

Yongjia Feng, Laura A. Johnson, Martin C. Clasby, Peter Higgins

This study tests a gut-selective Axl inhibitor, CCG264341, in vitro and in vivo models of intestinal fibrosis, finding it reduces fibrosis markers and Axl signaling.

bioRxiv · Mar 30, 2025 · PreprintImmunology

An organoid and multi-organ developmental cell atlas reveals multilineage fate specification in the human intestine

Qianhui Yu, Umut Kilik, Emily M. Holloway, Yu-Hwai Tsai, Angeline Wu, Joshua H. Wu, Michael J. Czerwinski, Charlie J. Childs, Zhisong He, Ian A. Glass, Peter Higgins, Barbara Treutlein, Jason R. Spence, J. Gray Camp

The paper uses human intestinal organoids to create a single-cell transcriptome atlas, revealing molecular mechanisms of cell fate specification in the intestine.

bioRxiv · Jul 24, 2020 · PreprintDevelopmental Biology