B7-H3 Modulates Cell Adhesion and Immune Evasion to Promote Tumor Progression and Natural Killer Cell Resistance in Hepatocellular Carcinoma
San Ha Han, Yoo Jin Cheon, Hyun Min Lee, Hyosun Seo, Ji Yoon Lee, Minjung Kim, Suk Ran Yoon, Dongho Choi, Chun Jeih Ryu
This study shows B7-H3 promotes HCC tumor progression by enhancing cell adhesion and immune evasion, particularly by reducing NK cell cytotoxicity.
bioRxiv · Mar 31, 2026 · PreprintCancer Biology