Exploiting single-cell quantitative data to map genetic variants having probabilistic effects
Florent Chuffart, Magali Richard, Daniel Jost, Helene Duplus-Bottin, Yoshikazu Ohya, Gael Yvert
This paper introduces a method to detect genetic variants with probabilistic effects on cellular traits using single-cell data, showing improved detection of linkages missed by classical genetic mapping.
PLOS Genetics · Aug 1, 2016Peer-reviewedGenetics