PD-1 negatively regulates helper T cell differentiation into Th2
Masaki Tajima, Naoko Ikuta, Yuka Nakajima, Kensuke Suzuki, Yosuke Tokumaru, Peng Li, Hiroshi Kiyonari, Tasuku Honjo, Akio Ohta
This study shows PD-1 inhibits Th2 cell differentiation and allergic inflammation in mice, suggesting its therapeutic potential for Th2-driven diseases.
bioRxiv · Jul 26, 2024 · PreprintImmunology