Long Reads Capture Simultaneous Enhancer-Promoter Methylation Status for Cell-type Deconvolution
Sapir Margalit, Yotam Abramson, Hila Sharim, Zohar Manber, Surajit Bhattacharya, Yiwen Chen, Eric J. N. Vilain, Hayk Barseghyan, Ran Elkon, Roded Sharan, Yuval Ebenstein
The paper develops a method to deconvolve cell-type mixtures using enhancer-promoter methylation profiles from long-read data, achieving higher accuracy than promoter-based approaches.
Bioinformatics · Apr 25, 2021Peer-reviewedBioinformatics