Surajit Bhattacharya

This study shows that the D2-mdx mouse model exhibits juvenile-onset cardiac damage due to unresolved inflammation, and pro-resolution therapy can mitigate fibrotic degeneration.

This study shows that Down Syndrome impairs type III IFN response and increases proinflammatory mediators in airway epithelial cells during RSV infection, leading to severe inflammation.

The paper identifies a frameshift mutation in Pkhd1 causing a cystic liver phenotype in mice and shows alternative splicing leads to reduced Pkhd1 protein levels and attenuated renal cystic disease.

The paper identifies DNA methylation and gene expression differences in the hypothalamus of rams with different sexual partner preferences, finding three genes associated with sexual behaviors.

The paper identifies DNA methylation changes linked to cyanogenic cassava exposure and konzo in Sub-Saharan Africa.

The paper develops a method to deconvolve cell-type mixtures using enhancer-promoter methylation profiles from long-read data, achieving higher accuracy than promoter-based approaches.

nanotatoR annotates structural variants using OGM data, providing comprehensive information for pathogenicity assessment and variant prioritization.