Combined assessment of MHC binding and antigen expression improves T cell epitope predictions
Zeynep Koşaloğlu‐Yalçın, Jenny Lee, Morten Nielsen, Jason Greenbaum, Stephen Philip Schoenberger, Aaron M. Miller, Young J Kim, Alessandro Sette, Bjoern Peters
This paper improves T cell epitope predictions by combining MHC binding affinities with antigen expression levels, showing better performance than methods using only binding or expression data.
bioRxiv · Nov 9, 2020 · PreprintBioinformatics