Young Je Lee

SpaTRACE: Spatiotemporal recurrent auto-encoder for reconstructing signaling and regulatory networks from spatiotemporal transcriptomics data

SpaTRACE jointly infers gene regulatory networks and cell-cell signaling from spatial transcriptomics data, outperforming existing methods in synthetic benchmarks and revealing novel interactions in development and regeneration.

scResolve: Recovering single cell expression profiles from multi-cellular spatial transcriptomics

scResolve recovers single-cell expression profiles from multi-cellular spatial transcriptomics data, enabling cell type-specific analysis and rare population detection in human tissues.